Molecular Nutrition and Genomics Laboratory
Department of Food Science and Nutrition
University of Minnesota - Twin Cities
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Selected Publications

  1. Guo H, Zhang Y, Hahn W, Brockman DA, Bernlohr DA, and Chen X.  Lipocalin 2 deficiency alters estradiol production and estrogen receptor signaling in female mice.  Endocrinology 153(3):1183-1193, 2012.
     
  2. Brockman DA and Chen X.   Proteomics in the characterization of adipose dysfunction in obesity.  Adipocyte 1(1):1-13, 2012.(Invited Review)
     
  3. Jin D, Guo H, Bu SY, Zhang Y, Hannaford J, Mashek DG, and Chen X.   Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditure.  FASEB J. 25(2):754-764, 2011.
     
  4. Zhang Y and Chen X.   Reducing selenoprotein P expression suppresses adipocyte differentiation as a result of increased preadipocyte inflammation.  American Journal of Physiology - Endocrinology and Metabolism 300(1):77-85, 2011.
     
  5. Jin D, Zhang Y, and Chen X.   Lipocalin 2 deficiency inhibits cell proliferation, autophagy, and mitochondrial biogenesis in mouse embryonic cells.  Molecular and Cellular Biochemistry 351(1):165-172, 2011.
     
  6. Guo H, Jin D, Zhang Y, Wright W, Bazuine M, Brockman DA, Bernlohr DA, and Chen X.  Lipocalin 2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in mice.  Diabetes 59(6):1376-1385, 2010.
     
  7. Ding L, Jin D, and Chen X.  Luteolin Enhances Insulin Sensitivity via Activation of PPARgamma Transcriptional Activity in adipocytes.  Journal of Nutritional Biochemistry 21(10): 941-947, 2010.
     
  8. Wu Y, Sun H, Mejia W, Novosyadlyy R, Nunez N, Chen X, Mendoza A, Hong S, Khanna C, Brodt P, Yakar S.  IGF-1 regulates the liver microenvironment in obese mice and promotes liver metastasis.  Cancer Research 70(1):57-67, 2010.
     
  9. Chen X , Hunt D, Cushman SW, and Hess S.  Proteomic Characterization of Thiazolidindione Regulation of Obese Adipose Secretome in Zucker Obese Rats.  Proteomics - Clinical Applications 3(9):1099-1111, 2009.
     
  10. Zhang J, Wu YJ, Zhang Y, LeRoith D, Bernlohr DA, and Chen X.  The Role of Lipocalin 2 in the Regulation of Inflammation in Adipocytes and Macrophages. Molecular Endocrinology 22(6):1416-26, 2008.
     
  11. Chen X and Hess S. Adipose Proteome Analysis: the Focus on Mediators of Insulin Resistance. Expert Review of Proteomics 5(6):827-39, 2008.(Invited Review)
     
  12. Hess S and Chen X.  Applications of Proteomics to the Study of Adipose Tissue. In: Adipose Tissue Protocols, 2nd ed., Humana Press (2008).
     
  13. Zhang J, Wright W, Bernlohr DA, Cushman SW, and Chen X.  Alterations of the Classic Pathway of Complement in Adipose Tissue of Obesity and Insulin Resistance.  American Journal of Physiology - Endocrinology and Metabolism 292(5):1433-40, 2007.
     
  14. Xiang CC, Wu YJ, Ma L, Ding L, Lisinski I, Brownstein MJ, Cushman SW, and Chen X.  Characterization of Insulin Resistant Phenotype of Cultured Primary Rat Adipose Cells.   Diabetologia 50(5):1070-9, 2007.
     
  15. Chen X, Pannell L, Cushman SW and Hess S.  Quantitative Proteomic Analysis of the Secretory Proteins from Adipose Cells Using a 2D Liquid Chromatography-MS/MS Approach.   Journal of Proteome Research 4(2):570-7, 2005.
     

 
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