The Machinery of Life (2nd Edition) by David S. Goodsell
The Machinery of Life is an excellent introduction to molecular biology. The book uses concise text and beautiful illustrations to reveal the mechanisms of the molecular machines in every life, making you wonder at the achievements of these invisible molecules.
The unique features of this book are the watercolor paintings that display the cellular interiors with all the molecular machines presented with scientific rigor. These paintings can be seen as the "snapshots" of the cell at high magnification (1,000,000X). The author carefully chose the composition so that the desired molecular machines and the relationship between them are clearly revealed. Some paintings are more than snapshots: they are smartly designed to show certain processes occurring in the cell, such as the death of a cell and the life cycle of a virus. These paintings can be thought as movie frames that are seamlessly fused together.
Besides these paintings, space-filling computer renderings are used to illustrate the detailed structures and functions of the molecular machines. Two kind of styles are used. One is the unique style used by the author for the Molecule of the Month series at Protein Data Bank (PDB). Molecules rendered with this style has a hand-drawing appearance, and blend seamless with the watercolor paintings. The other style is commonly used by scientists to illustrate the atomic structures and interactions of small molecules. Personally I think these renderings are too computer-like, and do not fit in very well with other illustrations. But this is a very minor complaint.
Dr. Goodsell is a master of using color to present scientific images. The colors are chosen so well that on the one hand the information is clearly communicated, and on the other hand the illustration are pleasant to eyes.
Overall, this is a wonderful book. I have been a fan for Dr. Goodsell for a long time, collecting many of his articles and drawings. And this book certainly makes me happy because of its interesting contents, beautiful illustrations, and affordable price. Anyone who is interested in the molecular biology or the visual presentation of biomolecules should read this book. (06/28/09)
Cover of The Machinery of Life