Smith APL, et al. (2002) DNA-Damage-Independent
Checkpoints: Yeast and higher eukaryotes. Cell Cycle 1(1):17-33
Complete List of Publications
| Clarke DJ, O'Neill LP, Turner BM | Clarke DJ, et al. (1993) Selective use of H4 acetylation
sites in the yeast Saccharomyces cerevisiae. Biochem J 294:557-61 |
| Clarke DJ, Johnson RT, Downes, CS | Clarke DJ, et al. (1993) Inhibitors of topoisomerase II
prevent anaphase chromatid separation independently of the generation
of DNA double strand breaks. J Cell Sci 105:563-569 |
| Clarke DJ, Johnson RT, Downes, CS | Clarke DJ, et al. (1994) Cytotoxicity of ionizing radiation in mammalian mitotic cells - topoisomerase II as a potential target. In Molecular mechanisms in radiation induced mutagenesis and carcinogenesis. Chadwick, K.H., Cox, R., Leenhouts, H. and Thacker, J. (Eds). Radiation protection series, EC 15294. pp113-116 |
| Downes CS, Clarke DJ, Mullinger AM, Gimenez-Abian JF, Creighton AM, Johnson RT | Downes CS, et al. (1994) A topoisomerase II-dependent
G2 cycle checkpoint in mammalian cells. Nature 372:467-470 |
| Gimenez-Abian JF, Clarke DJ, Downes CS, Mullinger AM, Johnson RT | Gimenez-Abian JF, et al. (1995) A post-prophase topoisomerase
II-dependent chromatid core separation step in the formation of metaphase
chromosomes. J Cell Biol 131(1):7-17 |
| Gimenez-Abian JF, Clarke DJ | Gimenez-Abian JF and Clarke DJ (1995) Cell Cycle: Checkpoints. Scientific American 226:40-41 |
| Downes CS, Clarke DJ, Tonnies H, Gimenez-Abian JF, Mullinger AM, Sperling K, Johnson RT | Downes CS, et al. (1996) Generation of partial monosomies in human somatic cells by inhibition of mitotic DNA topoisomerase II. In Proceedings on Chromosome Segregation and Aneuploidy, Abbondandolo A, Vig BK, Roi R (Eds). IST Press |
| Mondesert G, Clarke DJ, Reed SI | Mondesert G, et al. (1997) Identification of genes controlling
growth polarity in the budding yeast Saccharomyces cerevisiae: a possible
role of N-glycosylation and involvement of the exocyst complex. Genetics
147(2):421-34 |
| Gimenez-Abian JF, Clarke DJ, Garcia de la Vega C, Gimenez-Martin G | Gimenez-Abian JF, et al. (1997) The role of sister-chromatid
cohesiveness and chromosome structure in meiotic behaviour. Chromosoma
106(7):422-434 |
| Clarke DJ, Gimenez-Abian JF, Tonnies H, Neitzel H, Sperling K, Downes CS, Johnson RT | Clarke DJ, et al. (1998) Creation of
monosomic derivatives of human cultured cell lines. Proc Natl Acad
Sci USA 95(1):167-171 |
| Segal M, Clarke DJ, Reed SI | Segal M, et al. (1998) Clb5-associated kinase activity
is required early in the spindle pathway for correct preanaphase nuclear
positioning in Saccharomyces cerevisiae. J Cell Biol 143(1):135-45 |
| Kaiser P, Moncollin V, Clarke DJ, Watson MH, Bertolaet BL, Reed SI, Bailly E | Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1
interact with the proteasome in yeast to control proteolysis of M-phase
targets. Genes Dev 13(9):1190-202 |
| Gimenez-Abian JF, Clarke DJ, De la Torre C, Gimenez-Martin G, Mullinger AM, Downes CS, Johnson RT | Gimenez-Abian JF, et al. (1999) Competence for assembly
of sister chromatid cores is progressively acquired during S phase in
mammalian cells. Eur J Cell Biol 78:601-603 |
| Clarke DJ, Segal M, Mondesert G, Reed SI | Clarke DJ, et al. (1999) The Pds1 anaphase inhibitor and
Mec1 kinase define distinct checkpoints coupling S phase with mitosis
in budding yeast. Curr Biol 9(7):365-8 |
| Segal M, Clarke DJ, Maddox P, Salmon ED, Bloom K, Reed SI | Segal M, et al. (2000) Coordinated spindle assembly and
orientation requires Clb5p-dependent kinase in budding yeast. J Cell
Biol 148(3):441-52 |
| Gimenez-Abian JF, Clarke DJ, Devlin J, Gimenez-Abian MI, De la Torre C, Johnson RT, Mullinger AM, Downes CS | Gimenez-Abian JF, et al. (2000) Premitotic chromosome
individualization in mammalian cells depends on topoisomerase II activity.
Chromosoma 109(4):235-244 |
| Clarke DJ, Gimenez-Abian JF | Clarke DJ and Gimenez-Abian JF (2000) Checkpoints
controlling mitosis. Bioessays 22(4):351-63 |
| Jensen S, Segal M, Clarke DJ, Reed SI | Jensen S, et al. (2001) A Novel Role of the Budding Yeast
Separin Esp1 in Anaphase Spindle Elongation. Evidence that proper spindle
association of esp1 is regulated by pds1. J Cell Biol 152(1):27-40 |
| Clarke DJ, Mondesert G, Segal M, Bertolaet BL, Jensen S, Wolff M, Henze M, Reed SI | Clarke DJ, et al. (2001) Dosage suppressors of pds1 implicate
ubiquitin-associated domains in checkpoint control. Mol Cell Biol
21(6):1997-2007 |
| Clarke DJ, Smith APL, Gimenez-Abian JF | Clarke DJ, et al. (2001) DNA-Damage-Independent Checkpoints from Yeast to Man. In Cell Cycle Checkpoints and Cancer. Blagosklonny MV (Ed). Landes Bioscience, Georgetown, TX, USA |
| Segal M, Clarke DJ | Segal M and Clarke DJ (2001) The Ras Pathway and Spindle
Assembly Collide? (Mini-Review). BioEssays 23(4):307-310 |
| Bertolaet BL, Clarke DJ, Wolff M, Watson MH, Henze M, Divita G, Reed SI | Bertolaet BL, et al. (2001) UBA domains of DNA damage-inducible
proteins interact with ubiquitin. Nat Struct Biol 8(5):417-22 |
| Bertolaet BL, Clarke DJ, Wolff M, Watson MH, Henze M, Divita G, Reed SI | Bertolaet BL, et al. (2001) UBA Domains Mediate Protein-Protein
Interactions Between Two DNA Damage-inducible Proteins. J Mol Biol
313(5):955-63 |
| Clarkle DJ, Segal M, Jensen S, Reed SI | Clarke DJ, et al. (2001) Mec1p regulates Pds1p levels
in S phase: complex coordination of DNA replication and mitosis. Nat
Cell Biol 3(7):619-27 |
| Gimenez-Abian JF, Clarke DJ, Gimenez-Abian MI, De la Torre C, Gimenez-Martin, G | Gimenez-Abian JF, et al. (2001) Synchronous
nuclear envelope breakdown and anaphase onset in plant multinucleate cells.
Protoplasma 218(3-4):192-202 |
| Haase SB, Clarke DJ | Haase SB and Clarke DJ (2001) A Festival of Cell Cycle
Controls. Trends Cell Biology 11(11):445-6 |
| Smith APL, Gimenez-Abian JF, Clarke DJ | Smith APL, et al. (2002) DNA-Damage-Independent
Checkpoints: Yeast and higher eukaryotes. Cell Cycle 1(1):17-33
|
| Gimenez-Abian JF, Weingartner M, Binarova P, Clarke DJ, Anthony RG, Calderini O, Heberle-Bors E, Moreno Diaz de la Espina S, Bogre L, De La Torre C. | Gimenez-Abian JF, et al. (2002) A Topoisomerase II-dependent
Checkpoint in G2-phase Plant Cells can be bypassed by Ectopic Expression
of Mitotic Cyclin B2. Cell Cycle 1(3):187-192 |
| Clarke DJ | Clarke DJ (2002) Proteolysis & The Cell Cycle.
Cell Cycle 1(4):233-234 |
| Gimenez-Abian JF, Clarke DJ, Gimenez-Martin G, Weingartner M, Gimenez-Abian MI, Carballo JA, Moreno Diaz de la Espina S, Bogre L, De la Torre C | Gimenez-Abian JF, et al. (2002) DNA catenations that
link sister chromatids until the onset of anaphase are maintained by a
checkpoint mechanism. Eur J Cell Biol 81:9-16 |
| Clarke DJ | Clarke DJ (2002) Mitosis. Cell Cycle In Press
|
| Clarke DJ | Clarke DJ (2003) Establishment of dependence relationships
between genome replication and mitosis. (Review Article). J Cell Biochem
88(1):95-103 |
| Gimenez-Abian JF and Clarke DJ | Gimenez-Abian JF and Clarke DJ (2003) Replication-coupled
topoisomerase II activity templates the mitotic chromosome scaffold? Cell
Cycle 2(3):230-232 |
| Clarke DJ, Segal M, Andrews CA, Rudyak SG, Jensen S, Smith K and Reed SI | Clarke DJ, et al (2003) S-phase Checkpoint Controls
Mitosis via an APC-independent Cdc20p Function. Nature Cell Biol.
5(10):928-35
|
| Diaz-Martinez L and Clarke DJ | Diaz-Martinez L and Clarke DJ (2003)
Self-regulating model for control of replication origin firing in budding
yeast. Cell Cycle 2(6):576-8
|
| Andrews CA, Segal M, Reed SI & Clarke DJ | Andrews CA, Segal M, Reed SI & Clarke DJ (2004) Cdc20 in S-phase: The Banquo at Replication's Banquet. Cell Cycle 3(3):
276-279. |
| Squires S, Coates JA, Goldberg M, Toji LH, Jackson SP, Clarke DJ & Johnson RT | Squires S, et al (2004) p53 Prevents the Accumulation
of Double-Strand DNA Breaks at Stalled-Replication Forks Induced by UV
in Human Cells. Cell Cycle 3(12): 1543-1557. |
| Andrews CA and Clarke DJ | Andrews CA and Clarke DJ (2005) MRX (Mre11/Rad50/Xrs2)
mutants reveal dual intra-S-phase checkpoint systems in budding yeast.
Cell Cycle 4:(8):1073-1077. |
| Gimenez-Abian JF, Diaz-Martinez LA, Wirth K, Andrews CA, Gimenez-Martin G and Clarke DJ | Gimenez-Abian JF, et al. (2005) Regulated Separation of Sister Centromeres depends on the Spindle Assembly Checkpoint but not on the Anaphase Promoting Complex/Cyclosome. Cell Cycle 4(11): 1559-1573. |
| Gimenez-Abian JF, Diaz-Martinez LA, Waizenegger IC, Gimenez-Martin G and Clarke DJ | Gimenez-Abian JF, et al. (2005) Separase is required at multiple pre-anaphase cell cycle stages in human cells. Cell Cycle, 4(11): 1574-1582. |
| Gimenez-Abian JF, Diaz-Martinez LA, Wirth K, De la Torre C and Clarke DJ | Gimenez-Abian JF, et al. (2005) Proteasome activity is required for centromere separation independently of securin degradation in human cells. Cell Cycle 4(11): 1556-1558. |
| Andrews CA, Gimenez-Abian JF, Diaz-Martinez LA, Guacci V, Vas AV and Clarke DJ | Andrews CA, et al. (2005) Evidence that the yeast spindle assembly checkpoint has a target other than the anaphase promoting complex. Cell Cycle 4(11): 1553-1555. |
| Clarke DJ, Diaz-Martinez LA and Gimenez-Abian JF | Clarke DJ, et al. (2005) Anaphase promoting complex or Cyclosome? Cell Cycle 4(11): 1583-1590. |
| Kang Y, Vossler R, Diaz-Martinez LA, Winter NS, Clarke DJ and Walters KJ | Kang et al. (2006) UBL/UBA ubiquitin receptor proteins bind a common tetraubiquitin chain. J Mol Biol, 356(4):1027-1035. |
| Andrews CA, Vas A, Meier B, Gimenez-Abian JF, Diaz-Martinez LA, VanderWaal K, Hsu WS, Erickson S & Clarke DJ | Andrews et al. (2006) A Mitotic Topoisomerase II Checkpoint in Budding Yeast is required for Genome Stability but acts independently of Pds1/Securin. Genes & Dev. 20: 1162-1174 |
| Raveendranathan M, Chattopadhyay S, Bolon YT, Haworth J, Clarke DJ & Bielinsky AK | Raveendranathan et al. (2006) Genome-Wide Replication Profiles of S Phase Checkpoint Mutants Reveal Fragile Sites in Yeast. EMBO J. in press |