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Adrian P L Smith Honorary Member |
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| Curriculum Vitae |
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| Education • B.Sc., Biophysical Science (First Class with Hons.), University of East London • Ph.D., Cambridge University, Dept. Clinical Biochem., Hypoxic regulation of preproendothelin-1 and nitric oxide synthase type III expression in the lung. • Post-Doctoral, Mentor: Prof. S.I. Reed. Scripps Research Institute, La Jolla, CA, 1997-2003 |
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| Publications 1. Hadley, A. G., Leader, K., Laundy, G. J., Smith, A. P. L., Klouda, P. and Bradley, B. (1991) A rapid solid-phase rosette-inhibition assay for the detection of Fc receptor (FcRII)-blocking alloantibodies. Immunology letters. 27:215-220. 2. Smith, A. P. L. and Smith, K. G. V. (1991): Some insect records from Tanera More, Summer Isles, Ross (Scotland). The Entomologists Monthly Magazine. 127:p34. (Short taxonomic note). 3. Sogni, P., Smith, A. P. L., Gadano, A., Lebrec, D. & Higenbottam, T. W. Induction of nitric oxide synthase II does not account for excess vascular nitric oxide production in experimental cirrhosis. (1997) Journal of Hepatology. 26:1120-1127. 4. Maniscalco, M., Sofia, M., Smith, A., Demoncheaux, E. A. G., Mormile, M., Faraone, S. and Higenbottam, T. (1997) Lack of effect of nitric oxide inhibition on bronchial tone and metacholine-induced broncoconstriction in man. Respiratory Medicine. 91:335-340. 5. Gonzalez, A-M., Smith, A. P. L., Emery, C. J. and Higenbottam, T. W. (1997) Pulmonary Hypertension, family and environment. Journal of Human Hypertension. 11:559-561. 6. Gonzalez, A-M., Smith, A. P. L., Emery, C. J. and Higenbottam, T. W. (1998) The pulmonary hypertensive Fawn-Hooded rat has a normal serotonin transporter coding sequence. American Journal of Respiratory Cell and Molecular Biology 19: 245-249. 7. Katayama, Y., Higenbottam, T. W., Cremona, G., Akamine, S., Demoncheaux, E. A. G., Smith, A. P. L. and Siddons, T. E. (1998) Minimising the inhaled dose of NO with breath-by-breath delivery of spikes of concentrated gas. Circulation. 98: 2429-2432. 8. Higenbottam, T., Marriott, H., Siddons, T., Smith, A. P. L. (1998) Primary and secondary pulmonary hypertension Seminars In Respiratory And Critical Care Medicine. 19: 91-95. 9. Spruck, C, Strohmaier, H., Watson, M., Smith, A. P. L., Ryan, A., Krek, W. and Reed, S. I. (2001) A CDK-independent function of mammalian Cks1: targeting of SCFSkp2 to the CDK inhibitor p27Kip1. Molecular Cell. 7(3):639-50. 10. Spruck, C., de Miguel, M. P., Smith, A. P. L., Ryan, A., Stein, P., Schultz, R. M., Lincoln, A. J., Donovan, P. J., and Reed, S. I. (2002) Cks2 is essential for metaphase/anaphase transition in mammalian meiosis. Science. 300(5619):647-50. 11. Smith, A. P. L., Gimenez-Abian, J. and Clarke, D. J., (2002) DNA-Damage-independent checkpoints from yeast to man. Cell Cycle 1: 16-33. 12. Clarke, D. J., Smith, A. P. L. and Gimenez-Abian, J. (2002) DNA-Damage-independent checkpoints from yeast to man. In: Cell cycle checkpoints. Ed. M. Blagosklonny. Landes Bioscience, Austin USA. 13. Smith, A. P. L., Demoncheaux, E. A. G. and Higenbottam T. W. (2002) Nitric oxide gas decreases endothelial-1 mRNA in cultured pulmonary artery endothelial cells. Nitric Oxide. 6(2):153-159. 14. Demoncheaux, E. A. G., Higenbottam, T. W., Foster, P. J., Smith, A. P. L., Marriott, H. M., Bee, B., Akamine, S., and Davies Michael B. (2002) Circulating nitrite anions are donors for nitric oxide. Clinical Science (Lond). 102(1):77-83. 15. Demoncheaux, E. A. G., Foster, P. J., Borland, C. D., Smith, A. P. L., Higenbottam, T. W., and Davies Michael B. (2003) Determination of trace concentrations of dissolved nitric oxide in a biological buffer. The Analyst. 128:1281-1285. 16. Smith, A. P. L., Henze, M., Osborn, K. G., Lee, J. A., Bortner, D. M., Rosenberg, M. P. and Reed, S. I. (2003) Switching of melanocyte pigmentation associated with pars intermedia tumors revealed in yellow pelage Rb+/- and p27-/- female mice. Comparative Medicine. 53(1):75-80. |
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