Masano T. Sugiyama

B.S., University of Arizona
Chemical Engineering 2004

Ph.D. Candidate, Chemical Engineering
University of Minnesota

sugiy002@umn.edu

 

Research

Crystallization of Proteins in a Micro-fluidic CRYMA

Developing a continuous feed crystallization method that permits sampling of a wider range of conditions (than traditional methods), increasing the likelihood of obtaining a high quality crystal. Using this micro-fluidic technique with a modification that allows an electric field to be imposed upon the crystal, to increase crystal quality by “pre-aligning” macromolecules in a preferred direction. Extend the use of the imposed E-field with selective modification of an inert site on a protein to increase the electric dipole, to increase alignment