PubH 8341 - Advanced Epidemiologic Methods


Syllabus

Last updated: 9/1/2011 [PDF]



Reading list

Modern Epidemiology

Online access [UMN login required]

Hernan MA, Robins JM. Causal Inference.

Chapters 1-10 [PDF]

Intro to epi inference

Taubes G. Do we really know what makes us healthy? New York Times. New York, 2007. [PDF]

Lehrer J. The truth wears off. The New Yorker. New York, 2010. [PDF]

* Hernan MA. Invited commentary: hypothetical interventions to define causal effects--afterthought or prerequisite? Am J Epidemiol 2005;162:618-20; discussion 621-2. [PDF]

* Kaufman JS, Cooper RS. Seeking Causal Explanations in Social Epidemiology. American Journal of Epidemiology 1999;150:113-120. [PDF]

Counterfactuals

Little RJ, Rubin DB. Causal effects in clinical and epidemiological studies via potential outcomes: concepts and analytical approaches. Annu Rev Public Health 2000;21:121-45. [PDF]

Dawid AP. Counterfactuals: help or hindrance? Int J Epidemiol 2002;31:429-30. [PDF] [Note this paper starts after Maldonado's paper]

* Maldonado G, Greenland S. Estimating causal effects. Int J Epidemiol 2002;31:422-38. [PDF]

* Holland PW. Statistics and Causal Inference. Journal of the American Statistical Association 1986;91:945-960. [PDF]

Causal effects in observational studies

Rosenbaum PR. From Association to Causation in Observational Studies: The Role of Tests of Strongly Ignorable Treatment Assignment. J Am Stat Assoc 1984;79:41-48. [PDF]

Greenland S, Robins JM. Identifiability, exchangeability, and epidemiological confounding. Int J Epidemiol 1986;15:413-9. [PDF]

Greenland S, Robins JM. Identifiability, exchangeability and confounding revisited. Epidemiol Perspect Innov 2009;6(1):4 [PDF] [HTML]

* Oakes JM, Johnson PJ. Propensity score matching methods for social epidemiology. Pp. 370-392 in Methods in Social Epidemiology, Oakes JM, Kaufman JS, eds. San Francisco: Jossey-Bass, 2006 [PDF]

* Becher H. The concept of residual confounding in regression models and some applications. Stat Med 1992;11:1747-58. [PDF]

* Manski CF. Identification problems in the social sciences and everyday life. Southern Economic Journal 2003;70:11-21. [PDF]

Directed acyclic graphs

Robins JM. Data, design, and background knowledge in etiologic inference. Epidemiology 2001;12:313-320. [PDF]

Confounding

Greenland S, Morgenstern H. Confounding in health research. Annu Rev Public Health 2001;22:189-212. [PDF]

Hernan MA, Hernandez-Diaz S, Werler MM, Mitchell AA. Causal knowledge as a prerequisite for confounding evaluation: an application to birth defects epidemiology. Am J Epideiol 2002;155:176-84. [PDF]

*Hernan MA, Clayton D, Keiding N. The Simpson's paradox unraveled. Int J Epidemiol 2011;40:780-5. [PDF]

Selection bias

*Cole SR, Platt RW, Schisterman EF, Chu H, Westreich D, Richardson D, Poole C. Illustrating bias due to conditioning on a collider. Int J Epidemiol 2010;39:417-20. [PDF]

Measurement bias

Dosemeci M, Wacholder S, Lubin JH. Does nondifferential misclassification of exposure always bias a true effect toward the null value? Am J Epidemiol 1990;132:746-8. [PDF]

* Flegal KM, Keyl PM, Nieto FJ. Differential misclassification arising from nondifferential errors in exposure measurement. Am J Epidemiol 1991;134:1233-44. [PDF]

* Jurek AM, Greenland S, Maldonado G, Church T. Proper interpretation of non-differential misclassification effects: expectations vs. observations. Int J Epidemiol 2005;34:680-7. [PDF]

Effect modification / interaction / moderation

Greenland S. Basic problems in interaction assessment. Environ Health Perspect 1993:101 Suppl 4:59-66. [PDF]

* VanderWeele TJ. Sufficient cause interactions and statistical interactions. Epidemiology 2009;20:6-13. [PDF]

Mediation

Robins JM, Greenland S. Identifiability and exchangeability for direct and indirect effects. Epidemiology 1992:3:143-55. [PDF]

Cole SR, Hernan MA. Fallibility in estimating direct effects. Int J Epidemiol 2002;31:163-5. [PDF]

Kaufman JS, Maclehose RF, Kaufman S. A further critique of the analytic strategy of adjusting for covariates to identify biologic mediation. Epidemiol Perspect Innov 2004;1:4 [PDF]

Hypothesis testing, p-values and precision

Poole C. Low P-values or narrow confidence intervals: which are more durable? Epidemiology 2001;12:291-4. [PDF]

Rothman KJ. Curbing type I and type II errors. Eur J Epidemiol 2010;25:223-4. [PDF]

Stang A, Poole C, Kuss O. The ongoing tyranny of statistical significance testing in biomedical research. Eur J Epidemiol 2010;25:225-30. [PDF]

Goodman S. A dirty dozen: twelve p-value misconceptions. Semin Hematol 2008;45:135-40. [PDF]

* Hoenig JM, Heisey DM. The Abuse of Power: The Pervasive Fallacy of Power Calculations for Data Analysis. The American Statistician 2001;55:19-24. [PDF]

* Oakes JM. Statistical Power and Sample Size: Considerations for Clinician-Researchers. in Essentials of Clinical Research, edited by Stephen P Glasser. New York: Springer. In press [PDF]

* Savitz DA, Tolo KA, Poole C. Statistical significance testing in the American Journal of Epidemiology, 1970-1990. Am J Epidemiol 1994;139:1047-52. [PDF]

Instrumental variables

Glymour MM. Natural experiments and instrumental variable analyses in social epidemiology. In: Methods in Social Epidemiology, Oakes JM, Kaufman JS, eds. San Francisco: Jossey-Bass / Wiley, 2006:423-445. [PDF]

Hernan MA, Robins JM. Instruments for causal inference: an epidemiologist's dream? Epidemiology 2006;17:360-72. [PDF]

Bayesian theory and analysis

Greenland S. Bayesian perspectives for epidemiological research: I. Foundations and basic methods. Int J Epidemiol 2006;35:765-75 [PDF]

Greenland S. Bayesian perspectives for epidemiological research. II. Regression analysis. Int J Epidemiol 2007;36:195-202 [PDF]

* Western B. Bayesian Analysis for Sociologists: An Introduction. Sociological Methods & Research 1999;28:7-34 [PDF]

* Gurrin LC, Kurinczuk JJ, Burton PR. Bayesian statistics in medical research: an intuitive alternative to conventional data analysis. J Eval Clin Pract 2000;6:193-204 [PDF]

Group randomized trials

Feldman HA, Proschan MA, Murray DM, Goff DC, Stylianou M, Dulberg E, McGovern PG, Chan W, Mann NC, Bittner V. Statistical design of REACT (Rapid Early Action for Coronary Treatment), a multisite community trial with continual data collection. Control Clin Trials 1998;19:391-403. [PDF]

Hannan PJ Experimental social epidemiology: Controlled community trials." Pp. 335-364 in Methods in Social Epidemiology, edited by J. Michael Oakes and Jay S. Kaufman, 2006. San Francisco: Jossey-Bass / Wiley. [PDF]

Randomized clinical trials

Fisher LD. Advances in clinical trials in the twentieth century. Annu Rev Public Health 1999;20:109-24. [PDF]

DeMets DL. Statistical issues in interpreting clinical trials. J Intern Med 2004;255:529-37. [PDF]

* Kaufman JS, Kaufman S, Poole C. Causal inference from randomized trials in social epidemiology. Soc Sci Med 2003;57:2397-409. [PDF]

Review of cohort and case-control studies

Knol MJ, Vandenbroucke JP, Scott P, Egger M. What do case-control studies estimate? Survey of methods and assumptions in case-control research. Am J Epidemiol 2008;168:1073-81. [PDF]

Hybrid study design

Barlow WE, Ichikawa L, Rosner D, Izumi S. Analysis of case-cohort designs. J Clin Epidemiol 1999;52:1165-72. [PDF]

Maclure M, Mittleman M. Should we use a case-crossover design? Annu Rev Public Health 2000;21:193-221. [PDF]

Observational multilevel studies

Diaz Roux AV. Multilevel analysis in public health research. Annu Rev Public Health 2000;21:171-92. [PDF]

Oakes JM. The (mis)estimation of neighborhood effects: causal inference for a practicable social epidemiology. Soc Sci Med 2004;58:1929-52. [PDF]

Ecologic studies

Wakefield J. Ecologic studies revisited. Annu Rev Public Health 2008;29:75-90 [PDF]

Greenland S. Ecologic versus individual-level sources of bias in ecologic estimates of contextual health effects. Int J Epidemiol 2001;30:1343-50 [PDF]


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