Koob Lab Homepage
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Koob Lab Homepage |
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Michael Koob, Ph.D.
Assitant Professor Institute of Human Genetics and Dept. of Lab Medicine & Pathology University of Minnesota koobx001@umn.edu |
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Office: 5-215 Moos Tower Lab: 5-214 Moos Tower Mailing address: |
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Kellie Benzow |
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Koob, M.D., K.A. Benzow, T.D. Bird, J. W. Day, M.L. Moseley, and L.P.W. Ranum. Rapid cloning of expanded trinucleotide repeat sequences from genomic DNA. Nature Genetics 18, 72-75, 1998. [Abstract]
Koob, M.D., K.A. Benzow, T.D. Bird, M.L. Moseley, J. Day, L.J. Schut, and L.P.W. Ranum. An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8). Nature Genetics 21, 379-384, 1999. [PDF Reprint]
Nemes, J.P., Benzow, K.A., Moseley, M.L. Ranum, L.P., and Koob, M.D. The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1) Hum. Mol. Genet. 9, 1543-1551, 2000. [PDF Reprint]
Benzow, K.A., and Koob, M.D. The KLHL1-antisense transcript (KLHL1AS) is evolutionarily conserved. Mammalian Genome 13, 134-141, 2002.
Yu, B.J., Sung, B.H., Koob, M.D., Lee, C.H., Lee, J.H., Lee, W.K., Kim, M.S., and Sun Chang Kim, S.C. Minimization of the Escherichia coli genome using a Tn5-targeted Cre/loxP excision system. Nature Biotech. 20, 1018-1023, 2002.
Benzow, K.A., Koob, M.D., Condie, A., Catovsky, D., Matutes, E., Yuille, M.R., Houlston, R.S. Instability of CAG-trinucleotide repeats in chronic lymphocytic leukemia. Leukemia & Lymphoma 43, 1987-1990, 2002.
Yoon, Y.G., and Koob, M.D. Efficient cloning and engineering of entire mitochondrial genomes in Escherichia coli and transfer into transcriptionally active mitochondria. Nucleic Acids Research 31, 1407-1415. 2003.
